Homeostatic Soil Organisms™ Clinical Studies
Years ago, our soil was teeming with beneficial
microorganisms, called probiotics, which humans
consumed through their food. Today, however, the use
of pesticides, herbicides and other chemicals
has virtually eliminated the beneficial probiotic
content from our diets.
To replenish the valuable nutrients our modern diet
fails to provide, Garden of Life utilizes a
proprietary process to cultivate super probiotics
called Homeostatic Soil Organism™ blends, or HSOs™.
HSOs are considered "super" probiotics
because they are grown in a base of nutrient-rich Superfoods, providing more than 100 naturally
occurring live enzymes, vitamins, minerals, amino
acids, antioxidants, chlorophyllins and plant saponins.
Much more than a defense, the HSO blends in select
Garden of Life™ products literally attack the
harmful pathogens in the intestines to help eliminate
populations of yeast, parasites and bad bacteria.
Unlike other probiotics, HSOs can thrive in the
toughest digestive environments and are undeterred by
temperature, stomach acid, chlorine, fluorine,
ascorbic acid or bile.
In 1993, three single-blind,
placebo-controlled studies on HSOs™ were conducted
at the Dispensario Medico, Partido de la Revolucion
Democratica, a medical dispensary in Irapuato, Mexico.
The researchers wanted to find out whether Homeostatic
Soil Organisms™ could help people with high
cholesterol and leukemia. They also wanted to see if
the HSOs™ made test subjects feel more energetic and
improved memory and concentration.
* High
cholesterol: Seventy patients with blood cholesterol
counts higher than 300 milligrams per deciliter were
given HSOs or a placebo. Subjects given the HSOs™
saw their total blood cholesterol count drop by 25
percent or more; the placebo subjects showed no
change.
* Energy
levels, memory and concentration: Seventy patients
with no known pathologies were given Homeostatic Soil Organism™
or a
placebo. Thirty-three of the 35 subjects given HSOs™
reported feeling more energetic and vital. HGB
(hemoglobin) levels and red blood cell counts
increased moderately in 33 subjects. In the placebo
group, no subjects reported an increase in energy or
vitality levels. Only two subjects out of 33 (two
subjects dropped out of the study) saw their HGB
levels increase. In only one subject did the red blood
cell count increase. Conspicuous increases in memory
and concentration improved in 28 out of 35 test
patients with only 1 improving in the placebo group.
* Chronic
Lymphocytic Leukemia stage II: Thirty-five subjects
with chronic lymphocytic leukemia (CLL) were given
HSOs™. The director of research reported that HSOs
"attenuated the symptoms of approximately 80
percent of the treated patients." In 80 percent
of the subjects, white blood cell counts improved.
Results from additional studies:
* In a
study conducted at Bio Inova Life Sciences
Laboratories under the direction of Pierre Braquet,
PhD. and Jean Michel Mencia-Juerta, PhD., researchers
attempted to identify the anti-microbial properties of
Primal Defense™ HSOs™. The HSOs™ were found to
be effective in inhibiting various pathogenic
microorganisms, including Psuedomonus aeruginosa, a
disease-causing microorganism.
* Another
study conducted at Bio Inova Life Sciences
Laboratories evaluated the effectiveness of Primal
Defense™ Homeostatic Soil Organism™ on the immune system. In this
study, researchers looked at natural killer (NK) cells
and macrophage function. Natural killer cells roam the
bloodstream looking for and destroying foreign-invader
cells. Macrophages are large white blood cells that
also serve the immune system by killing foreign
invaders. In the study, Primal Defense™ HSOs™ were
found to boost the immune system by enhancing the
function of natural killer cells and macrophage
function.
* In
another study at Bio Inova Life Sciences Laboratories,
Primal Defense™ HSOs™ were examined with a view
toward how they affect cancer cells. The HSOs™ were
shown to inhibit the proliferation of cancer cells in
the breast, liver and lung.
* In
another study at Bio Inova Life Sciences Laboratories,
Primal Defense™ HSOs™ were shown to enhance the
production of healthy cells in the colon which may
positively effect those suffering from severe
digestive disorders, and oxidative stress.
* In an
open-label, 120-day clinical pilot study conducted by
Paul A. Goldberg, M.P.H, D.C. at the Goldberg Clinic
in Marietta, Georgia, 16 individuals suffering from
complex digestive and immune-system disorders were
given Primal Defense™ HSOs™ for 120 days. The
subject’s gastrointestinal and immune system
disorders had been resistant to conventional and
complimentary treatments. They had a variety of
chronic diseases that were unresponsive to medical
intervention for a minimum of three years. The
subjects ranged in age from 20 to 65. No dietary or
lifestyle changes were made. Fifteen of the 16
subjects reported clinical improvements in their
overall health. They had partial to full relief from
troublesome bowel problems, decreases in asthmatic
symptoms, increases in energy levels, improvements in
skin conditions, improvement in chronic sinus
infection, and general improvement in overall
well-being. No subjects reported a worsening of their
symptoms. Eight of nine subjects with elevated yeast
levels as verified by stool and/or blood tests had a
significant reduction in Candida yeast growth. Three
subjects with asthma had a 50 percent or greater
reduction in usage of inhalant medications and asthma
symptoms. One subject, a physician with chronic
pulmonary fungal infection, reported greater ease in
breathing and improvement in spirometer readings as
evidenced by her medical pulmonologist. Moreover,
three subjects who suffered from long-term chronic
constipation and had laxative dependency were able to
move their bowels daily without the use of laxatives.
Three subjects with chronic IBS showed between 25 and
100 percent improvement. Four patients with chronic
fatigue syndrome were completely free of symptoms by
the end of the 120-day period. Before and after blood
tests and physical examinations showed that no subject
experienced a worsening of conditions or exhibited any
evidence of toxicity.
Clinical placebo controlled studies were conducted at
the Peoples University of the Americas in Ponce,
Puerto Rico.
* A
90-day, 70-patient, blind placebo-controlled clinical
study published in Progress in Nutrition, evaluated
the effectiveness of Primal Defense™ Homeostatic Soil Organism™
as a
primary treatment for chronic digestive disorder and
malabsorption syndrome. Thirty-one patients in the
study group and 14 patients in the placebo group
completed the study. Some 52 percent of those taking
Primal Defense™ achieved full remission of symptoms;
32 percent of the participants achieved greater than
40 percent improvement of symptoms; no subjects had
zero improvement of symptoms or a worsening of
symptoms.
According to the director of the study, Primal Defense™
qualifies as an accomplished therapy with
"significant efficacy" for treating chronic
digestive disorders coupled with malabsorption
syndrome.
Additional
data from studies conducted on Primal Defense™ HSOs
showed the following results:
1) Individuals consuming Primal
Defense™ HSOs had a marked increase in blood levels
of several key enzymes including Amylase, Lipase and
Protease.
2) After consuming Primal Defense™
HSOs™, 18 individuals with low blood protein levels
at the beginning of the study had an increase in blood
protein levels which signifies improved absorption and
utilization of protein from the diet.
3) Individuals consuming Primal
Defense™ Homeostatic Soil Organism™ had a marked improvement in
symptoms of anemia and the use of the product seemed
to have a "blood building" effect.
4) Individuals consuming Primal
Defense™ HSOs™ had a marked improvement in blood
levels of key minerals.
5) Individuals consuming Primal
Defense™ HSOs™ with abnormal immune markers showed
a trend towards a modulation of the immune system as
evidenced by a decrease in White Blood Cells an
increase in Neutrophiles a normalization of
Lymphocytes and a decrease in elevated Monocytes,
Eosinophiles and Basophiles.
In addition, a significant number of
beneficial observations were made in the course of the
studies. These were beyond the scope of the
established protocol and therefore were not
incorporated into the official reports published in
Progress in Nutrition:
*
Fourteen patients (nine females, five males) reported
remarkable increases in their energy levels beginning
toward the end of the second month and continuing
through the full course of treatment.
* Three
female patients having suffered from chronic,
recurrent migraine headaches, reported total remission
from their headaches by study’s end.
* Six
patients (five females, one male) having suffered from
various grades of chronic skin rash, reported total
remission of these symptoms.
* Six patients (four
females, two males) reported significant vanishing of
some of their facial wrinkles by the end of the study.
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